Christopher R. Cogle, M.D., is a professor in the University of Florida College of Medicine. He is a physician, scientist, and educator with clinical, research, and policy focus on cancer. Dr. Cogle earned his medical degree, specialized in internal medicine, and subspecialized in medical oncology at the University of Florida. He then completed a fellowship in stem cell biology and blood & marrow transplantation at Duke University. In 2004, he was recruited to the faculty at University of Florida to create a translational research program in blood cancers. Dr. Cogle led a research team to discover blood vessels serve as a sanctuary site for refractory blood cancers, invented two new therapeutics, and translated the new treatments back to his patients. Dr. Cogle is also a consulting oncologist at the Malcolm Randall Department of Veterans Affairs Medical Center, with disease focus on blood cancers in the Veteran population.
In medical science, Dr. Cogle is credited with several major discoveries and inventions including:
Discovered that hematopoietic stem cells make brain cells in humans (Lancet 2004);
Discovered that blood vessels are sanctuary sites for blood cancers and lead to relapsed cancer (Leukemia 2014);
Discovered that myocardial infarctions poison the bone marrow through inflammatory cytokine signaling and prevent hematopoietic stem/progenitor cells from repairing the heart (Circulation Research 2014);
Invented and patented two new drug classes to treat cancer patients;
Invented and patented a new method of using an oncolytic virus (myxoma virus) to kill human cancers and prevent graft versus host disease (Leukemia 2009, Blood 2015);
Invented two new methods to accurately count cancer cases in the US (Blood 2011, Leukemia Research 2014); and
Developed a new computational biology and digital drug simulation method of interpreting the hundreds of DNA mutations inside a cancer cell to tailor treatment for cancer patients (Leukemia Research 2017, Blood Cancer Journal 2019).
Dr. Cogle has published over 100 articles in peer-reviewed medical journals and written in 3 scholarly textbooks.
The Leukemia & Lymphoma Society has distinguished Dr. Cogle as a Scholar in Clinical Research. The MDS International Foundation has designated Dr. Cogle's clinic a Center of Excellence in the Myelodysplastic Syndromes.
In teaching, Dr. Cogle has trained over 50 mentees who serve on faculty and in industry throughout the world. He invented two new nationally recognized methods of teaching cancer to trainees.
Writing and storytelling fascinate Dr. Cogle. He directs two literature courses to undergraduate students at the University of Florida: Physician Writers in the Post-Modern Era, and Literature, Illness, and the Outwardly Healthy Reader. Dr. Cogle is a frequent invited contributor to newspapers, raising public awareness to urgent issues in health and medicine.
Civic engagement is a priority to Dr. Cogle. He is an Eagle Scout and Vigil Honor of the Order of the Arrow. Dr. Cogle is a Den Leader in Cub Scout Pack 416, where his two sons and two daughters share in the adventures and lifelong lessons of Scouting. As a vocal advocate for patients, Dr. Cogle has produced two documentaries (cinemed.org) for public screening parties to discuss and correct disparities in health care. He serves on the Florida Medial Association Council on Medical Education and Science, where he directs the scientific program at annual meetings and advises on state medical education and science issues.
Dr. Cogle is the elected State Chairperson of the Florida Cancer Control and Research Advisory Council (CCRAB), where he leads the state’s cancer planning, coordination among stakeholders, and Cancer Plan implementation. CCRAB is charged with advising the Florida State Legislature, State Surgeon General, and Governor on ways to reduce Florida's cancer burden.
Dr. Cogle has served as the National Chairman of the American Medical Association's Medical Student Section and its Resident and Fellow Section. He was a founding member of the American Society Hematology Trainee Council and its first Chairperson. Later in his career, he served on two Scientific Committees in the American Society of Hematology. Dr. Cogle has also served as an ex officio member of the National Cancer Policy Forum, where he participated in and led national workshops on pressing issues in health and medicine.